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Table 1 Characteristics of included methods

From: Reviewing methodological approaches to dose-response modelling in complex interventions: insights and perspectives

Authors

Year

Method

Study Design

Sample

Control arm

Lutz, Martinovich & Howard13

1999

Multilevel Modelling

Observational

Routine Care

No

Anderson & Lambert14

2001

Survival Analysis – Kaplan-Meier

Observational

Routine Care

No

Imbens15

2000

Propensity Score Matching

Observational

Not applicable

No

Steenland & Deddens16

2004

Smoothing Splines

Observational

Not applicable

No

Flores17

2007

Kernel Regression

Observational

Not applicable

No

Maracy & Dunn18

2011

Structural Mean Model + G-estimation

RCT

Clinical trial participants

Yes

Maracy & Dunn18

2011

2 stage Instrumental Variables

RCT

Clinical trial participants

Yes

Ginestet, Emsley & Landau19

2017

Instrumental Variables – Stein like estimators

RCT

Clinical trial participants

Yes