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Table 3 Distribution of the 26 analyzed comorbidities in myocardial infarction patients across defined clusters

From: Multiple states clustering analysis (MSCA), an unsupervised approach to multiple time-to-event electronic health records applied to multimorbidity associated with myocardial infarction

Cluster number

1

2

3

4

5

6

7

8

9

10

11

Total

Cancer

316 (31.1)

65 (10.2)

94 (14.8)

72 (13.6)

84 (16.3)

29 (7.9)

53 (15.5)

44 (13.6)

60 (19.1)

41 (17.4)

22 (12.8)

880 (17.3)

Stroke

261 (25.7)

100 (15.7)

88 (13.9)

71 (13.4)

87 (16.9)

61 (16.7)

33 (9.6)

59 (18.3)

33 (10.5)

35 (14.8)

26 (15.1)

854 (16.8)

Heart Failure

314 (30.9)

158 (24.8)

120 (18.9)

152 (28.6)

150 (29.2)

114 (31.1)

111 (32.5)

95 (29.4)

114 (36.3)

77 (32.6)

50 (29.1)

1455 (28.6)

Peripheral Vascular Disease

144 (14.2)

72 (11.3)

65 (10.2)

58 (10.9)

37 (7.2)

74 (20.2)

50 (14.6)

40 (12.4)

25 (8.0)

34 (14.4)

18 (10.5)

617 (12.1)

Atrial Fibrillation

201 (19.8)

70 (11.0)

77 (12.1)

119 (22.4)

134 (26.1)

44 (12.0)

72 (21.1)

77 (23.8)

83 (26.4)

42 (17.8)

17 (9.9)

936 (18.4)

Hypertension

657 (64.6)

510 (80.1)

317 (49.9)

523 (98.5)

396 (77.0)

262 (71.6)

133 (38.9)

222 (68.7)

139 (44.3)

169 (71.6)

88 (51.2)

3416 (67.2)

Transient Ischemic Attack

73 (7.2)

40 (6.3)

25 (3.9)

67 (12.6)

37 (7.2)

25 (6.8)

19 (5.6)

23 (7.1)

19 (6.1)

14 (5.9)

9 (5.2)

351 (6.9)

Viral Hepatitis (B & C)

34 (3.3)

11 (1.7)

9 (1.4)

2 (0.4)

0 (0.0)

4 (1.1)

1 (0.3)

3 (0.9)

0 (0.0)

5 (2.1)

3 (1.7)

72 (1.4)

Rheumatoid Arthritis

58 (5.7)

7 (1.1)

14 (2.2)

8 (1.5)

12 (2.3)

7 (1.9)

3 (0.9)

9 (2.8)

7 (2.2)

2 (0.8)

5 (2.9)

132 (2.6)

IBDa

43 (4.2)

8 (1.3)

6 (0.9)

6 (1.1)

3 (0.6)

1 (0.3)

4 (1.2)

6 (1.9)

4 (1.3)

1 (0.4)

8 (4.7)

90 (1.8)

CKDb 3–5

303 (29.8)

137 (21.5)

104 (16.4)

178 (33.5)

198 (38.5)

115 (31.4)

67 (19.6)

89 (27.6)

98 (31.2)

99 (41.9)

32 (18.6)

1420 (27.9)

Liver Disease

16 (1.6)

6 (0.9)

30 (4.7)

7 (1.3)

3 (0.6)

9 (2.5)

0 (0.0)

3 (0.9)

4 (1.3)

4 (1.7)

5 (2.9)

87 (1.7)

Anxiety Disorders

213 (20.9)

155 (24.3)

325 (51.2)

86 (16.2)

65 (12.6)

44 (12.0)

32 (9.4)

49 (15.2)

25 (8.0)

24 (10.2)

65 (37.8)

1083 (21.3)

Depression

288 (28.3)

136 (21.4)

474 (74.6)

69 (13.0)

57 (11.1)

81 (22.1)

38 (11.1)

40 (12.4)

37 (11.8)

33 (14.0)

81 (47.1)

1334 (26.2)

Alcohol Dependence

56 (5.5)

45 (7.1)

218 (34.3)

31 (5.8)

6 (1.2)

14 (3.8)

9 (2.6)

6 (1.9)

4 (1.3)

3 (1.3)

22 (12.8)

414 (8.1)

Serious Mental Illness

83 (8.2)

20 (3.1)

50 (7.9)

11 (2.1)

5 (1.0)

9 (2.5)

2 (0.6)

2 (0.6)

2 (0.6)

1 (0.4)

6 (3.5)

191 (3.8)

Substance Use (Dependency)

59 (5.8)

12 (1.9)

67 (10.6)

4 (0.8)

6 (1.2)

6 (1.6)

4 (1.2)

1 (0.3)

2 (0.6)

1 (0.4)

19 (11.0)

181 (3.6)

Diabetes

314 (30.9)

240 (37.7)

206 (32.4)

131 (24.7)

110 (21.4)

365 (99.7)

124 (36.3)

111 (34.4)

89 (28.3)

235 (99.6)

67 (39.0)

1992 (39.2)

Obesity (morbidly obese)

61 (6.0)

83 (13.0)

36 (5.7)

27 (5.1)

13 (2.5)

46 (12.6)

28 (8.2)

32 (9.9)

11 (3.5)

27 (11.4)

27 (15.7)

391 (7.7)

Osteoarthritis

323 (31.8)

134 (21.0)

140 (22.0)

134 (25.2)

134 (26.1)

76 (20.8)

69 (20.2)

317 (98.1)

81 (25.8)

79 (33.5)

28 (16.3)

1515 (29.8)

Osteoporosis

59 (5.8)

5 (0.8)

24 (3.8)

28 (5.3)

63 (12.3)

6 (1.6)

11 (3.2)

25 (7.7)

23 (7.3)

14 (5.9)

2 (1.2)

260 (5.1)

Parkinson’s

27 (2.7)

5 (0.8)

10 (1.6)

9 (1.7)

9 (1.8)

3 (0.8)

5 (1.5)

4 (1.2)

4 (1.3)

6 (2.5)

0 (0.0)

82 (1.6)

Epilepsy

103 (10.1)

23 (3.6)

13 (2.0)

7 (1.3)

1 (0.2)

1 (0.3)

6 (1.8)

4 (1.2)

4 (1.3)

2 (0.8)

6 (3.5)

170 (3.3)

Dementia

134 (13.2)

20 (3.1)

37 (5.8)

50 (9.4)

107 (20.8)

11 (3.0)

33 (9.6)

38 (11.8)

46 (14.6)

27 (11.4)

6 (3.5)

509 (10.0)

Asthma

287 (28.2)

44 (6.9)

77 (12.1)

32 (6.0)

52 (10.1)

26 (7.1)

28 (8.2)

39 (12.1)

19 (6.1)

19 (8.1)

165 (95.9)

788 (15.5)

COPDc

265 (26.1)

42 (6.6)

133 (20.9)

66 (12.4)

60 (11.7)

21 (5.7)

86 (25.1)

49 (15.2)

44 (14.0)

25 (10.6)

48 (27.9)

839 (16.5)

Total N (%)

1017 (20.0)

637 (12.5)

635 (12.5)

531 (10.4)

514 (10.1)

366 (7.2)

342 (6.7)

323 (6.3)

314 (6.2)

236 (4.6)

172 (3.4)

5087

  1. a Inflammatory Bowel Disease
  2. b Chronic Kidney Disease stage 3 to stage 5
  3. c Chronic Obstructive Pulmonary Disease