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Table 4 Estimated parameters \(\hat{\varvec{\beta }}\) along with their 95% Confidence Intervals (CIs) for the Cox MSM in Eq. (7) and for the corresponding unweighted traditional Cox model

From: Causal effect of chemotherapy received dose intensity on survival outcome: a retrospective study in osteosarcoma

 

Cox MSM

Unweighted Cox model

 

Pseudo-population

Original population

Covariate

\(\hat{\varvec{\beta }}\)

95% CIs

\(\hat{\varvec{\beta }}_{\textbf{unw}}\)

95% CIs

\(a=1\)

\(-0.536\)

\([-1.031; -0.041]\)

\(-0.116\)

\([-0.568; 0.335]\)

\(a=2\)

\(-0.808\)

\([-1.384; -0.231]\)

\(-0.359\)

\([-0.844; 0.127]\)

\(a=1 \times V=1\)

0.747

\([-0.379; 1.873]\)

\(-0.006\)

\([-0.997; 0.984]\)

\(a=2 \times V=1\)

1.747

[0.554; 2.939]

0.979

[0.035; 1.923]

\(V=1\)

\(-1.909\)

\([-2.835; -0.981]\)

\(-1.175\)

\([-1.921; -0.429]\)